Endocrine Abstracts

Background: Dyslipidemia is a well-known manifestation of thyroid dysfunction and there is evidence of an association between hypothyroidism and coronary heart disease. Recently, small dense low-density lipoprotein (sdLDL) has been linked with development of cardiovascular disease. But relations between thyroid function and sdLDL remain incompletely understood.Objective: Our objective was to determine whether replacement therapy with thyroxine for patien...

Introduction: Primary aldosteronism (PA) is one of the common diseases, and aldosterone-producing adenoma (APA) is a surgically curable type, which is usually treated by unilateral total adrenalectomy. We had recently developed a new method of supper-selective ACTH-stimulated adrenal venous sampling (SS-ACTH-AVS) for exactly detecting the main lesion(s) of hyperaldosteronemia. Then we attempted to partially remove the unilateral lesion of hyperaldosteronism detected by SS-ACTH...

Introduction: It has been reported that primary aldosteronism(PA) is often associated with subclinical Cushing syndrome (SCS). In the present study, we investigated the frequency of SCS in subjects with PA.Method: Subjects included consecutive patients (n=43) who were diagnosed as PA between 2003 and 2011 in our institute. They were screened by plasma renin activity (PRA (ng/ml/h)) plasma aldosterone concentration (PAC (pg/mL)) ratio (ARR) above 2...